Herbal medicine has a long history of traditional use, throughout the world, for menstrual irregularities and fertility.  More recently, scientific research has been showing positive results for herbal and nutritional treatments for polycystic ovarian syndrome, and deepening our understanding of the underlying causes.  We now know that herbs and nutrients can be used to adjust levels of specific hormones and encourage the normal, healthy function of organs.  Teamed with modifying our diet and forming good habits in our daily lives, these therapies can form the basis of long-lasting hormonal change. 

Whilst there are some effective natural medicines available over the counter, herbs and nutrients are best prescribed by a trained Herbalist, Nutritionist or Naturopath (both Herbalist & Nutritionist).  When choosing a natural medicine practitioner look for someone with a sound education in Science and who is a member of a government-recognised Professional Association. This means that the practitioner is bound by a duty of care that ensures that they do no harm.  Ask to see their qualifications.  There are a range of treatments that your practitioner may select for you.  Here are my 10 favourite:

Herbal medicine

*Please note: herbal medicines may interact with medications and should not be taken concurrently without supervision of a trained practitioner.  If you become pregnant, cease taking herbal medicines and consult your practitioner.  Only take herbal preparations in the dose recommended on the label.  If in doubt consult your Naturopath or Herbalist.

1. Licorice & Peony

This herbal combination has a long history of use in Traditional Chinese Medicine and some evidence from small clinical trials.  I have seen great results in clinic with this combination and it returned my cycles to regular, years ago, when it was prescribed to me by my Naturopath.

How it works: it is thought that licorice and peony reduce testosterone (an androgen) by the blocking of enzymes involved in its production.  This may be why this combination can regulate the menstrual cycle.  

Cautions: whilst this is a generally safe treatment, there are many situations in which this herbal medicine combination should not be taken.  It is best prescribed by your Naturopath/Herbalist so that they can assess it's suitability and determine the right dose.  Definitely do not take if: you have high blood pressure, you are under 18, you are on fertility drugs, digoxin, corticosteroid drugs or blood pressure medication.  Not for long-term use.

2. Goat's rue

This is the blood sugar-lowering herb that the diabetes drug Metformin was based on.  It is excellent for sugar cravings.  It contains guanidine, which dimethylbiguanide was modelled off, to make Metformin.  Metformin is commonly prescribed as a treatment for PCOS.

How it works: it increases insulin sensitivity, thereby decreasing insulin resistance and androgen production.  In turn, this decreases PCOS symptoms.

Cautions: not to be taken with insulin or blood sugar-lowering drugs.  

3. Cinnamon

Most of us have this common household spice in our kitchen.  So throw it into cooking wherever possible.  I often use it in chia pudding, porridge or muesli.  However, it can also be delightful in savoury cooking!  For example, Yotam Ottolenghi uses loads of it in delicious savoury recipes.  Cinnamon can also be taken in liquid extract or capsule form, as prescribed by your Naturopath.

How it works: cinnamon enhances blood sugar control by reducing blood glucose levels and improving insulin sensitivity.  This decreases insulin levels, thereby reducing androgen secretion and PCOS symptoms.

Cautions: some people are allergic to cinnamon.  If you experience an allergy to cinnamon seek medical advice immediately.

4. Phellodendron

Phellodendron has a long history of use in Traditional Chinese Medicine.  It contains berberine, which has been studied for it's effects on blood glucose, PCOS, acne and diabetes.

How it works: berberine helps PCOS by lowering blood sugar, increasing insulin sensitivity and healing the gut.  In the clinic, I have found that Phellodendron is particularly great for acne.

Cautions: Not to be taken for longer than 3 months at a time.  This herb may interact with many medications so if you are taking any prescriptions please consult your Naturopath/Herbalist before taking Phellodendron. Also please note that the berberine content of Phellodendron products may vary, and this will change the effective dosage. So if you aren't getting the best results, contact your naturopath.

5. Rhodiola

Rhodiola has a history of traditional use in Eastern Europe and Asia and has long been a popular herb due to it's ability to help the body to cope with stress, improve mood, increase mental alertness (student's love it!), decrease fatigue and heighten endurance.  It is a wonderful herb and I use it all the time in clinic.

How it works: this herb decreases the stress hormone cortisol, thereby reducing insulin.  So you can see that stress is bad for PCOS.  I'll be explaining this further in my next post.

Cautions: it is important to also work on the underlying causes of your stress, both internal and external.  Rhodiola is an excellent tool to get you through periods of acute stress or to help come down from chronic stress.  However, it is best not to rely on it long-term but to take the opportunity it offers to make changes to your life and state of mind.


*Please note: if you become pregnant, all nutrient supplementation should be ceased and you should consult your primary care physician about what to take during your pregnancy.  Only take nutrient supplements at the dose recommended on the label of that particular product.  If in doubt consult your Naturopath or Doctor.

1. Inositol

There are 2 forms of inositol available as a supplement: Myo-inositol and D-chiro-inositol.  Both have shown great results in reducing symptoms of PCOS clinical trials.  These include reduction in acne & hirsutism, regulating the menstrual cycle and improving ovulation.

How does it work? Inositol reduces insulin and thereby reduces androgens.

Cautions: for best results this supplement should be taken 1/2hr before food and 2hrs away from caffeine.  Dosage is important.  Myo-inositol is effective at a dosage of 2g/day over 6 months.  D-chiro-inositol can be taken at a dose of 1000-1500mg.  However, always follow the directions on the label of your supplement and if in doubt consult your Naturopath or Doctor.

2. Chromium

Chromium is an essential trace nutrient that has been found to be crucial for blood sugar control.  There is evidence from clinical trials that chromium supplementation reduces blood sugar and insulin resistance in women with PCOS and Type 2 Diabetes.  Important: Chromium Picolinate is the type of chromium that has been shown to work in the clinical trials.  Not all chromium supplements are the same.

How it works: it is thought that chromium increases insulin sensitivity by binding to insulin receptors, thereby helping the body to use sugar from the blood, whilst reducing excess insulin in the blood.  If you are not sure why excess insulin is bad for PCOS, check out this post.

Cautions: chromium may reduce the need for blood sugar-lowering medications so consult your doctor before taking chromium if you are on these.

3. Magnesium

Not just any old magnesium.  Magnesium bisglycinate (also called magnesium amino acid chelate) is the most likely to give you a therapeutic effect because it is the most well absorbed in the gastrointestinal tract.  Magnesium is an important mineral for wellbeing, performing at least 300 different functions in the body including muscle relaxation and blood sugar regulation.  It is depleted by stress, caffeine and alcohol.

How it works: once again, magnesium combats insulin resistance.

Caution: poor forms of magnesium, whilst not harmful, may give you loose or watery bowel movements because your body can't absorb them.  This can however, be useful as a short-term treatment for constipation.

4. Vitamin D

Around one third of Australians are vitamin D deficient.  Have your vitamin D levels checked once per year.  If you are deficient you should supplement until your levels are corrected.

How it works: noticed a pattern here? You guessed it.  Vitamin D also works on insulin resistance.  As most of these treatments work on the same pathway, you can see why you don't need to be on all of them.  However, if you are vitamin D deficient this needs to be in your regime because vitamin D plays a myriad of other important roles in the body, including maintaining bone density and immune system function.

Cautions: vitamin D is a fat soluble vitamin which means that it gets stored in fat in the body. If you take too much, you can end up with toxicity.  Make sure you get your blood levels tested before you start supplementing and see your Naturopath or Doctor to determine which dose and duration of treatment is right for you.

5. Alpha-lipoic acid

Alpha-lipoic acid is an antioxidant that helps cells use glucose for energy.  It has had positive results in small clinical trials in both diabetic patients and patients with PCOS.

How it works: Alpha-lipoic acid assists the insulin signalling pathway, improving insulin sensitivity and reducing symptoms of PCOS.

Cautions: like chromium, alpha-lipoic acid may have an additive effect with blood sugar-lowering medications and decrease the need for them.  See your practitioner before beginning if you are on medication.

There are many more herbs and nutrients to choose from but these are some of the most commonly used and most effective.  They can help you get better results but they cannot replace the right diet.  Without a low sugar, low carbohydrate, anti-inflammatory diet, they are merely band-aids and when you stop taking them, your symptoms may return.  These natural medicines can help you get better results faster and with the support of the right diet, exercise and stress reduction they can help you keep PCOS in check, permanently.

All the best on your health journey,


For a comprehensive treatment solution and access to an exclusive support section, including email support from Melbourne Naturopath, Josephine, get The PCOS Solution.


Adam, TC, Hasson, RE, Ventura, EE, Toledo-Corral, C, Le, K-A, Mahurkar, S, Lane, CJ, Weigensberg, MJ & Goran, MI 2010, ‘Cortisol is negatively associated with insulin sensitivity in overweight Latino youth.’, The Journal of clinical endocrinology and metabolism, vol. 95, no. 10, pp. 4729–4735, <http://www.ncbi.nlm.nih.gov/pubmed/20660036>.

Allen, RW, Schwartzman, E, Baker, WL, Coleman, CI & Phung, OJ 2013, ‘Cinnamon Use in Type 2 Diabetes: An Updated Systematic Review and Meta-Analysis’, The Annals of Family Medicine, vol. 11, no. 5, pp. 452–459, <http://www.ncbi.nlm.nih.gov/pubmed/24019277>.

Alvarez, JA & Ashraf, A 2010, ‘Role of vitamin d in insulin secretion and insulin sensitivity for glucose homeostasis.’, International journal of endocrinology, vol. 2010, no. March 2009, p. 351-385, <http://www.ncbi.nlm.nih.gov/pubmed/20011094>.

Amooee, S & Parsanezhad, M 2013, ‘Metformin versus chromium picolinate in clomiphene citrate-resistant patients with PCOs: A double-blind randomized clinical trial’, Iranian Journal of …, vol. 11, no. 8, pp. 611–8, viewed 27 April 2014, <http://www.ncbi.nlm.nih.gov/pubmed/24639797>.

An, Y, Sun, Z, Zhang, Y, Liu, B, Guan, Y & Lu, M 2014, ‘The use of berberine for women with polycystic ovary syndrome undergoing IVF treatment’, Clinical Endocrinology, vol. 80, no. 3, pp. 425–431, <http://www.ncbi.nlm.nih.gov/pubmed/23869585>.

Armanini, D, Mattarello, MJ, Fiore, C, Bonanni, G, Scaroni, C, Sartorato, P & Palermo, M 2004, ‘Licorice reduces serum testosterone in healthy women.’, Steroids, vol. 69, no. 11-12, pp. 763–6, viewed 21 April 2014, <http://www.ncbi.nlm.nih.gov/pubmed/15579328>.

Bailey, CJ & Day, C 2004, ‘Metformin: Its botanical background’, Practical Diabetes International, vol. 21, no. 3, pp. 115–117, <http://thehumanpath.org/files/MetforminAndGalega.pdf>.

Bone, K & Mills, S 2013, Principles and Practices of Phytotherapy, 2nd edn., Elsevier, Churchill Livingstone, Sydney.

Daly, RM, Gagnon, C, Lu, ZX, Magliano, DJ, Dunstan, DW, Sikaris, KA, Zimmet, PZ, Ebeling, PR & Shaw, JE 2012, ‘Prevalence of vitamin D deficiency and its determinants in Australian adults aged 25 years and older: a national, population-based study’, Clinical Endocrinology, vol. 77, no. 1, pp. 26–35, <https://www.stayonyourfeet.com.au/wp-content/uploads/2015/03/Daly-et-al.-Vitamin-D-Deficiency-2011.pdf>.

Fouladi, RF 2012, ‘Aqueous extract of dried fruit of Berberis vulgaris L. in acne vulgaris, a clinical trial.’, Journal of dietary supplements, vol. 9, no. 4, pp. 253–61, <http://www.ncbi.nlm.nih.gov/pubmed/23038982>.

Guerrero-Romero, F, Tamez-Perez, H, González-González, G, Salinas-Martínez, A, Montes-Villarreal, J, Treviño-Ortiz, J & Rodríguez-Morán, M 2004, ‘Oral Magnesium supplementation improves insulin sensitivity in non-diabetic subjects with insulin resistance. A double-blind placebo-controlled randomized trial’, Diabetes & Metabolism, vol. 30, no. 3, pp. 253–258, <http://www.ncbi.nlm.nih.gov/pubmed/15223977>.

Kamenova, P 2006, ‘Improvement of insulin sensitivity in patients with type 2 diabetes mellitus after oral administration of alpha-lipoic acid.’, Hormones (Athens, Greece), vol. 5, no. 4, pp. 251–258, <http://www.ncbi.nlm.nih.gov/pubmed/17178700>.

Lydic, ML, McNurlan, M, Bembo, S, Mitchell, L, Komaroff, E & Gelato, M 2006, ‘Chromium picolinate improves insulin sensitivity in obese subjects with polycystic ovary syndrome.’, Fertility and sterility, vol. 86, no. 1, pp. 243–6, viewed 27 April 2014, <http://www.ncbi.nlm.nih.gov/pubmed/16730719>.

Magistrelli, A & Chezem, JC 2012, ‘Effect of ground cinnamon on postprandial blood glucose concentration in normal-weight and obese adults.’, Elsevier, Journal of the Academy of Nutrition and Dietetics, vol. 112, no. 11, pp. 1806–9, viewed 29 April 2014, <http://www.ncbi.nlm.nih.gov/pubmed/23102179>.

La Marca, A, Grisendi, V, Dondi, G, Sighinolfi, G & Cianci, A 2015, ‘The menstrual cycle regularization following D-chiro-inositol treatment in PCOS women: a retrospective study’, Gynecological Endocrinology, vol. 31, no. 1, pp. 52–56, <http://www.ncbi.nlm.nih.gov/pubmed/25268566>.

Martin, J & Wang, Z 2006, ‘Chromium Picolinate Supplementation Attenuates Body Weight Gain and Increases Insulin Sensitivity in Subjects With Type 2 Diabetes’, Diabetes …, vol. 29, no. 8, viewed 4 November 2013, <http://diabetes.publicaciones.saludcastillayleon.es/>.

Masharani, U, Gjerde, C, Evans, JL, Youngren, JF & Goldfine, ID 2010, ‘Effects of Controlled-Release Alpha Lipoic Acid in Lean, Nondiabetic Patients with Polycystic Ovary Syndrome’, Journal of Diabetes Science and Technology, vol. 4, no. 2, pp. 359–364, <http://www.ncbi.nlm.nih.gov/pubmed/20307398>.

Mooren, F., Kruger, K, Volker, K, Golf, S., Wadepuhl, M & Kraus, A 2011, ‘Oral magnesium supplementation reduces insulin resistance in non-diabetic subjects – a double-blind, placebo-controlled, randomized trial’, Diabetes, Obesity and Metabolism, vol. 13, pp. 281–284, <http://www.ncbi.nlm.nih.gov/pubmed/21205110>.

Nestler, JE & Unfer, V 2015, ‘Reflections on inositol(s) for PCOS therapy: steps toward success’, Gynecological Endocrinology, vol. 31, no. 7, pp. 501–505, <http://www.ncbi.nlm.nih.gov/pubmed/26177098>.

Sarris, J, McIntyre, E & Camfield, D a 2013, ‘Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence.’, CNS drugs, vol. 27, no. 4, pp. 301–19, viewed 29 April 2014, <http://www.ncbi.nlm.nih.gov/pubmed/23653088>.

Sarris, J, Panossian, A, Schweitzer, I, Stough, C & Scholey, A 2011, ‘Herbal medicine for depression, anxiety and insomnia: a review of psychopharmacology and clinical evidence.’, European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, vol. 21, no. 12, pp. 841–60, viewed 22 May 2013, <http://www.ncbi.nlm.nih.gov/pubmed/21601431>.

Spasov, AA, Wikman, GK, Mandrikov, VB, Mironova, IA & Neumoin, V V 2000, ‘A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen.’, Phytomedicine : international journal of phytotherapy and phytopharmacology, vol. 7, no. 2, pp. 85–89, <https://nootrobox.com/spasov-phytomedicine.pdf>.

Takahashi, K & Kitao, M 1994, ‘Effect of TJ-68 (shakuyaku-kanzo-to) on polycystic ovarian disease.’, International journal of fertility and menopausal studies, vol. 39, no. 2, pp. 69–76, viewed 24 April 2014, <http://www.ncbi.nlm.nih.gov/pubmed/8012442>.

Takahashi, K & Yoshino, K 1988, ‘Effect of a traditional herbal medicine (shakuyaku-kanzo-to) on testosterone secretion in patients with polycystic ovary syndrome detected by ultrasound.’, Nihon Sanka Fujinka Gakkai zasshi, vol. 40, no. 6, pp. 789 – 92, <http://www.ncbi.nlm.nih.gov/pubmed/3292675>.

Takeuchi, T, Nishii, O, Okamura, T & Yaginuma, T 1991, ‘Effect of paeoniflorin, glycyrrhizin and glycyrrhetic acid on ovarian androgen production.’, The American journal of Chinese medicine, vol. 19, no. 1, pp. 73–8, viewed 21 April 2014, <http://www.ncbi.nlm.nih.gov/pubmed/1897494>.

Wei, W, Zhao, H, Wang, A, Sui, M, Liang, K, Deng, H, Ma, Y, Zhang, Y, Zhang, H & Guan, Y 2012, ‘A clinical study on the short-term effect of berberine in comparison to metformin on the metabolic characteristics of women with polycystic ovary syndrome.’, European journal of endocrinology / European Federation of Endocrine Societies, vol. 166, no. 1, pp. 99–105, viewed 9 April 2014, <http://www.ncbi.nlm.nih.gov/pubmed/22019891>.

Yaginuma, T, Izumi, R, Yasui, H, Arai, T & Kawabata, M 1982, ‘Effect of traditional herbal medicine on serum testosterone levels and its induction of regular ovulation in hyperandrogenic and oligomenorrheic women (author’s transl).’, Nihon Sanka Fujinka Gakkai zasshi, vol. 34, no. 7, pp. 939–44, viewed 24 April 2014, <http://www.ncbi.nlm.nih.gov/pubmed/7108310>.

Zacchè, MM, Caputo, L, Filippis, S, Zacchè, G, Dindelli, M & Ferrari, A 2009, ‘Efficacy of myo-inositol in the treatment of cutaneous disorders in youngwomen with polycystic ovary syndrome.’, Gynecological endocrinology : the official journal of the International Society of Gynecological